Patrick Mahomes Odds to Win MVP: OTB as of December 2025

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Patrick Mahomes' MVP Odds, OPOY & More: December 2025

With the season entering Week 16, it’s the perfect time to size up Mahomes’ chances at MVP along with other key milestones. Unfortunately, Mahomes' odds are off the board after suffering a season-ending injury on December 14.

👑 Patrick Mahomes' MVP Odds:	OTB
🏆 Patrick Mahomes' OPOY Odds:	OTB
🏈 Most Regular Season Passing Yards:	OTB
🚀 Most Regular Season Passing TDs:	OTB
📆 Last Verified:	December 22, 2025

Note that odds for Patrick Mahomes and other NFL players will vary between MO betting apps and will fluctuate throughout the rest of the season. It’s always a good idea to shop around for the best numbers.

What Are Patrick Mahomes' Odds to Win MVP?

Patrick Mahomes’ MVP odds are off the board. Mahomes was a favorite throughout the first half of the season, but after being eliminated from the playoffs and suffering an ACL tear, he is no longer an MVP contender.

We’ll continue tracking the news cycle to get a clearer read on how sportsbooks view the NFL MVP race throughout the season.

Can Patrick Mahomes Win MVP?

No, Patrick Mahomes cannot win MVP. Even though he's led the Chiefs to seven straight AFC Championship Game appearances, his odds are now off the board with his season over.

MORE: Chiefs Super Bowl Odds

Has Patrick Mahomes Won the MVP?

Yes, Patrick Mahomes has won the NFL Most Valuable Player twice, in 2018 and 2022. He's also won the Super Bowl MVP award three times, in Super Bowl LIV, Super Bowl LVII, and Super Bowl LVIII. His combination of arm strength, ability to read defenses, and consistent play has made him one of the league’s premier quarterbacks and a perennial favorite in sports betting, keeping fans and bettors eager to see what he does next.

MORE: Chiefs Playoff Chances

How Many Times has Patrick Mahomes Won NFL MVP?

Patrick Mahomes has won the NFL MVP twice: in 2018 and 2022. Mahomes finished the 2018 season with 50 touchdowns and 5,097 passing yards. He led the league in passing yards and touchdowns in 2022, with 5,250 passing yards and 41 TDs. His remarkable ability to make big plays under pressure consistently draws attention both around the league and in sports betting markets.

What Are Patrick Mahomes' Offensive Player of the Year Odds?

Patrick Mahomes’ odds to win Offensive Player of the Year are also off the board. Historically the OPOY award tends to favor running backs over quarterbacks. A running back has claimed the award 26 times compared to 20 quarterbacks. WR Jaxon Smith-Njigba is the favorite to take it this year.

Has Patrick Mahomes Won Offensive Player of the Year?

Yes, Patrick Mahomes won NFL Offensive Player of the Year in 2018, his first season as the Chiefs’ starting quarterback. That same year, he also claimed his first MVP award. It was the last time a quarterback took home OPOY, and it marked the start of one of the most remarkable stretches in recent NFL history.

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Other Patrick Mahomes Odds and Props

Beyond Patrick Mahomes’ MVP odds, there are plenty of other props to keep an eye on throughout the NFL season, including over/under bets on passing yards, touchdowns, and more.

Patrick Mahomes' Passing Yards Props

Odds for Patrick Mahomes to throw for over 4,000+ passing yards total should be a popular pick, given his skill as a passer. He has surpassed 5,000 passing yards in a season twice in his career, making it reasonable to expect him to keep up that high level of production. These odds will differ across sportsbooks. In Week 12, Mahomes recorded his 50th career game with more than 300 passing yards. Odds are off the board for Mahomes after his injury.

🏈 4,000+ Regular Season Passing Yards:	OTB
🚀4,500+ Regular Season Passing Yards:	OTB
📆 Last Verified:	December 22, 2025

*Odds are from FanDuel

Patrick Mahomes' Passing TDs Props

Similar to his passing yards props, the odds for Patrick Mahomes to throw for over 30+ regular season touchdowns is usually a good bet. Mahomes threw an impressive 50 touchdowns in 2018, and with Kansas City’s high-powered offense, his passing touchdown odds remain a must-watch every season.

🏈 30+ Regular Season Passing TDs:	OTB
⭐ 35+ Regular Season Passing TDs:	OTB
🚀 40+ Regular Season Passing TDs:	OTB
📆 Last Verified:	December 22, 2025

*Odds are from FanDuel

Current Mahomes Stats

Below are Patrick Mahomes’ stats for the 2025–26 season.

🚀 Passing Yards:	3,587
🎯 Passing TDs:	22
💨 Rushing Yards:	422
🏈 Rushing TDs:	5
📆 Last Verified:	December 22, 2025

Patrick Mahomes celebrates Super Bowl win

Where to Bet on Patrick Mahomes' Odds

You can now bet on Patrick Mahomes’ odds in Missouri since sports betting is live. The following apps are among the top sportsbooks in the state, where you’ll be able to wager on Mahomes’ MVP odds, Offensive Player of the Year, passing yards, touchdowns, and more:

Final Thoughts on Patrick Mahomes MVP Odds

After the Chiefs’ Super Bowl loss to the Eagles, a 2025-26 “revenge tour” was expected with Mahomes leading the charge. Up until recently, Patrick Mahomes was firmly in the mix for a third MVP. He was named AFC Offensive Player of the Week after throwing for 270 yards and four touchdowns in the Week 4 win over the Ravens. But since, things have gone down hill for KC and Mahomes' odds are off the board. Los Angeles Rams' QB Matthew Stafford has the best odds to win MVP.

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Patrick Mahomes MVP Odds FAQ

Entering Week 16 of the season, Patrick Mahomes’ MVP odds are off the board. With a 6–8 record, the Kansas City Chiefs have been eliminated from the playoffs, and Mahomes suffered a season-ending injury, ending their postseason hopes.

Yes, Patrick Mahomes has won the NFL MVP award twice, in 2018 and 2022. In 2018, he threw for 5,097 passing yards and 50 touchdowns. Four years later, in 2022, he led the league again with 5,250 passing yards and 41 touchdowns.

Patrick Mahomes has already won three Lombardi Trophies: LIV, LVII, and LVIII. He earned Super Bowl MVP honors in each of them. In Super Bowl 58, he completed 34 of 46 passes for 333 yards, further cementing his status as the game’s biggest star.

Author

Wes Roesch

Editor & Writer

Wes is an editor and writer for BetMissouri.com. Based out of the Kansas City area, Wes has covered the Chiefs professionally since 2016, kickstarting the website Chiefs Wire for USA TODAY as the site's first managing editor. Since then, Wes has covered the Chiefs for other outlets, and has also covered sports betting, college sports, pro wrestling and more.

Patrick Mahomes MVP Odds, OPOY & Player Props