Betting on the Chiefs in MO: A Step-by-Step Guide
Sports betting is officially available in Missouri, and it’s worth knowing what to look for before placing your first NFL bets, especially on the hometown favorite, the Chiefs. With sports betting live, this guide serves as your playbook for making smarter wagers.
Pick an App
The first thing you have to do before placing any NFL or Chiefs bets is to decide which sportsbook you want to use. Luckily for you, you can check out our Missouri betting apps page, as well as individual brand reviews to figure out which operator(s) you want to go with.
If you stick to standard bets like moneylines and point spreads, the main difference between sportsbooks is the odds. But if you’re looking to place player props, alternate lines, or same-game parlays, it pays to compare sites, since market depth and pricing can vary.
Choose Your Wager
Because NFL betting is by far the most popular option across the US, you'll find some of the most expansive markets for football compared to other sports. Here are some of the most common bet types:
- Moneyline
- Spread
- Totals
- Parlays
- Prop bets
- Live betting
Before placing any wager, whether it's on the Chiefs, another NFL team, or a different sport altogether, be sure you understand how the market works. Moneylines are the most straightforward bet there is, while spread betting can be confusing to some at first.
For beginners, it’s wise to approach parlays with caution. While the idea of turning $5 into $5,000 is tempting, parlays are designed to be tough to hit, and that’s why sportsbooks profit the most from them and promote them heavily.
Missouri sports betting allows you to bet on futures such as the Chiefs playoff odds, Chiefs AFC Championship odds, Chiefs Super Bowl odds, and more.
What Are the Chiefs' Playoff Chances in 2025?
The Chiefs' odds to make the playoffs are off the board at DraftKings Missouri after they were eliminated from the playoffs in Week 15.
| 🔥 Chiefs Playoff Chances | OTB |
| 🏆 Chiefs Chances to Win Super Bowl LX | OTB |
| 👑 Chiefs Chances to Win AFC | OTB |
| 🥇 Chiefs Chances to Win AFC West | OTB |
| ⭐️ Patrick Mahomes Chances to Win MVP | OTB |
| 📆 Odds Last Verified | December 2025 |
Ahead of Week 17, the Chiefs’ AFC title odds are off the board at DraftKings Sportsbook. The Chiefs are missing the playoffs for the first time since 2014. With Mahomes going down with an injury, his MVP odds are also off the board. We will update the table above when odds become available for next season.
Choose Your Wager Amount
This is arguably the most important part of the process. When sizing your bets, the key advice is to choose an amount you’re comfortable losing and stick to it. Before placing any bet, imagine the money is already gone. If that thought makes you uneasy or unsure, it’s a sign to lower your wager.
Many sportsbooks also offer responsible gambling tools, like personalized settings where you can preset your bet amount. That way, when you’re ready, all you have to do is hit "Place Bet," helping you stay in control and avoid overspending.
MORE: Chiefs Super Bowl Odds
Author
Cody Kutzer has been covering the sports betting and gambling space for several years and has been losing his parlay bets for even longer. He currently serves as an editor, writer, and fact-checker for BetMissouri.com to ensure readers have the latest and most accurate information surrounding sports betting in the state.
