How to Bet on MLB in Missouri
If you're brand new to sports betting, the following breakdown will help you learn the ropes so you're ready to place your first MLB wager in Missouri when the time comes. For those with sports betting experience, it's a solid refresher that offers useful insights into how MLB betting works in the state.
With Missouri home to two MLB teams, the St. Louis Cardinals and Kansas City Royals, interest in baseball betting is already strong across the state. And with 162 regular-season games per team, MLB offers more betting opportunities than almost any other major sport.
1. Download An App
Before you can place a bet, you first have to figure out which sportsbook app you want to use. With the potential for up to 14 MO betting apps, this may seem like a daunting task. For the most part, every operator will have the basics covered when it comes to betting on the MLB in Missouri. As long as you're using a legal and licensed site, you really can't go wrong.
Which app you use will come down to personal preference. I always recommend signing up with multiple sportsbooks so you can compare odds before placing any wagers. Getting the best price means a better potential payout, and that can add up over time. Here are a few of my favorite things about the operators we expect to be available in Missouri:
- FanDuel MO - Best for beginners
- DraftKings - Best for player props and overall market variety
- Caesars MO - Best for odds boosts
- BetMGM MO - Best for localized experience
- bet365 - Best for early payouts
- Fanatics Sportsbook MO - Best for rewards program
This can serve as a solid starting point, but it’s a good idea to download each app and spend a few minutes exploring to see which one feels right for you. Most sportsbooks let you browse their platform without creating an account first.
2. Claim Your Welcome Offer
If this is your first time signing up for a particular operator, you'll be able to claim new user Missouri sportsbook promos. While this isn't required, there is generally no reason not to take advantage of these bonuses. The majority of bonuses typically require $5-$10 deposits and wagers, which is something most bettors would be doing anyway.
The DraftKings Missouri promo code will be popular, as MLB fans are likely to be familiar with the brand. Considering the branding you'll see when watching Cardinals games, the bet365 bonus code Missouri is sure to be a fan favorite as well.
Gambling problem? Call 1-800-GAMBLER (Available in the US) Call 877-8-HOPENY or text HOPENY (467369) (NY) Call 1-800-327-5050 (MA), 1-800-NEXT-STEP (AZ), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR) 21+ only. Please Gamble Responsibly. See http://BetMGM.com for Terms. First Bet Offer for new customers only. Minimum $10 deposit required. Bonus bets expire in 7 days. One new player offer. Add’l terms. Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. This promotional offer is not available in DC, Mississippi, New York, Nevada, Ontario, or Puerto Rico.-
Gambling problem? Call 1-800-GAMBLER. 21+. Physically present in Missouri. Eligibility restrictions apply. 1 per new customer. $5+ first-time bet req. Max. $300 issued as non-withdrawable Bonus Bets that expire in 7 days (168 hours). Stake removed from payout. Excludes customers who redeem prelaunch signup offer. Terms: http://sportsbook.draftkings.com/promos. Ends 1/4/26 at 11:59 PM CST. Sponsored by DK.
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GAMBLING PROBLEM? CALL OR TEXT 1-800-GAMBLER (AZ, CO, IN, IL, KS, KY, LA, MD, MO, NC, NJ, OH, PA, TN, VA) or 1-800-BETS OFF (IA). 21+ only (18+ in KY). Must be present in AZ/CO/IA/IN/KS/KY/LA (select parishes)/MD/MO/NC/NJ/OH/PA/TN/VA. T&Cs, time limits, and exclusions apply. Minimum $10 deposit required. Minimum odds -500 or greater. Bonus Bets wager excluded from returns. New customers only.
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Must be 21+ and physically present in MO. New users only. Must register using eligible promo code. Min. qualifying bet amount: $5. Min. Odds: -500. First wager after registration must qualify. Awarded as non-withdrawable Bonus Bets that expire 30 days after receipt. Bonus Bet amount not returned for winning bets. See Caesars Sportsbook or the Promotions tab on the app for full terms. Void where prohibited. Know When To Stop Before You Start®. Gambling Problem? Call 1-800-GAMBLER
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Gambling Problem? Call 1-800-GAMBLER or visit http://RG-help.com. Call 1-888-789-7777 or visit http://ccpg.org/chat (CT). Hope is here. http://GamblingHelpLineMA.org or call (800) 327-5050 for 24/7 support (MA). Visit http://www.mdgamblinghelp.org (MD). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY). Must be 21+ (18+ in D.C., KY, WY) and present in select states (for KS, in affiliation with Kansas Star Casino). Unique user identity verification required. First online real money wager only; $5 first deposit required. Bonus issued as non-withdrawable bonus bets that expire 7 days after receipt. Restrictions apply. See terms at http://sportsbook.fanduel.com.
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21+. New customers in AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA, MA, MD, MO, MI, NC, NJ, OH, PA, TN, VA, VT, WV, or WY (excludes NY). New customers who wager $10+ cash on any market with odds of -500 or longer are eligible to receive $100 in FanCash (“Rewards”) each day for your first three (3) days. You must wager $10+ each day to be eligible for the Rewards each day. FanCash issued under this promotion expires at 11:59 p.m. ET 7 days from issuance. Promotion ends at 11:59pm ET on December 31, 2025. Terms, incl. FanCash terms, apply—see Fanatics Sportsbook app. Gambling Problem? Call or Text 1-800-GAMBLER, 1-800-NEXT-STEP (AZ), 1-800-9-WITH-IT (IN), 1-888-532-3500 (VA).
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Must be 21+ to participate. T&Cs Apply. Play Responsibly. Gambling problem? Call 1-800-GAMBLER (CO, DC, IL, KY, LA, MD, MO, MS, NJ, OH, PA, VA, WV, WY), Call 1-800-9-WITH-IT (IN), Call 877-8-HOPENY or text HOPENY (467369) (NY). Call 1-800-NEXT-STEP (AZ), 1-800-522-4700 (KS), 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-270-7117 for confidential help (MI), Call 877-718-5543 or visit morethanagame.nc.gov. (NC), Call or Text 800-889-9789 (TN).
3. Find the Bet You Want to Place
As mentioned above, different operators offer varying levels of market depth across each sport, and MLB is no exception. Below is a list of the most popular types of MLB wagers, along with a brief explanation of how each one works:
- Moneyline: The most straightforward type of bet. You’re simply picking which team will win the game.
- Run Line: This is baseball’s version of a point spread. The run line is usually set at 1.5. If the Cardinals are -1.5, they need to win by 2 or more runs for your bet to hit. If they’re +1.5, they can lose by 1 run (or win outright), and your bet still wins.
- Totals (Over/Under): A wager on the total number of combined runs scored by both teams. If the total is set at 6.5, the over hits with 7 or more runs, while the under wins with 6 or fewer.
- Parlays: A parlay combines two or more bets (called “legs”) into a single wager. Parlays offer bigger payouts, but every leg must win for the ticket to cash. For example, if you build a 4-leg parlay, all four bets must hit.
- Props: MLB prop bets can focus on teams or individual players. Examples include the total number of strikeouts by the Cardinals or betting on whether Bobby Witt Jr. will hit a home run.
4. Determine Your Bet Size
While this step is often overlooked, it's one of the most important things you can do as a bettor. Your deposit size should guide how much you're wagering, not the other way around. Setting clear limits and sticking to them helps you manage your bankroll, avoid chasing losses, and make smarter betting decisions over time.
A well-managed bankroll can extend your betting activity and help you spot value more clearly, since you're betting with intention, not emotion.
Popular MLB Odds in MO
Here are a few popular MLB betting markets to watch as we enjoy the offseason, including who will win the World Series. All of the odds listed are from top sportsbooks including bet365 Missouri.
2026 Futures Odds
MLB Teams in Missouri
If you’re looking to bet on MLB teams in Missouri, you’ll be happy to know the Show-Me State is home to two pro clubs: the Kansas City Royals and the St. Louis Cardinals. The Royals last won the World Series in 2015, while the Cardinals’ most recent title came in 2011. Both teams entered 2025 as long shots to win it all, with the Dodgers ultimately taking the title again.
The Kansas City Royals have seen a resurgence lately, thanks in large part to the breakout of star shortstop Bobby Witt Jr. Kansas City made a surprise run to the playoffs in the 2024 MLB season but fell short in the Wild Card round against the New York Yankees. Even with a young and improving roster, the Royals’ failed to make the playoffs in the 2025 season. Make sure to follow along next season as we follow the Royals playoff chances.
The St. Louis Cardinals hold the second-most World Series titles in MLB history, trailing only the New York Yankees. But recent seasons haven’t lived up to that legacy. After missing the playoffs in 2024 and struggling with consistency, there’s not much buzz around St. Louis failed to advance to the postseason in 2025. Follow along next season as the team gets back on track in pursuit of another playoff berth with our Cardinals playoff chances page.
Missouri MLB Betting FAQs
Yes, you’ll be able to bet on MLB games in Missouri as soon as sports betting goes live in the Show-Me State on December 1. That includes full access to betting markets for all 30 teams, as well as local favorites like the Kansas City Royals and St. Louis Cardinals.
Missouri is home to two MLB franchises, the St. Louis Cardinals and the Kansas City Royals. Together, they’ve won 13 World Series titles, with the Cardinals accounting for 11 of them, making them one of the most successful teams in league history.
You must be at least 21 years old to bet on MLB games in Missouri. This age requirement applies to all sports and is consistent with legal sports betting laws in every state where it's allowed. You’ll also need to be physically located within Missouri state lines when placing your bets.
Yes. Once sports betting officially launches in MO on December 1, you'll be able to place MLB props on both teams and individual players. You will be able to stack MLB props in a large parlay to increase the possible winnings you might attain.
Author
Cody Kutzer has been covering the sports betting and gambling space for several years and has been losing his parlay bets for even longer. He currently serves as an editor, writer, and fact-checker for BetMissouri.com to ensure readers have the latest and most accurate information surrounding sports betting in the state.
